Research in the Bystriansky Lab is currently focused on the role and regulation of sodium pump isoforms. Some current/recent projects include:
The challenge of osmoregulating low temperaures. How do different sodium pump isoforms perform when it gets really cold? MS student Heidi Luczynski is working on answering this question.
Influence of hyperosmotic saline treatment on sodium transport mechanisms in epithelial cells. When lung and kidney epithelia are exposed to increased salinity, how do sodium pump isoforms respond? This question forms the basis of Michelle Sener’s MS thesis.
Osmoregulation and acid-base balance in the white sturgeon (Acipenser transmontanus) during exposure to aquatic hypercarbia and elevated salinity. When sturgeon are faced with these two environmental challenges at once, they prioritize salinity acclimation over acid-base balance. Read all about it in former MS student Ciaran Shaughnessey ‘s first publication.
Muscle Na+/K+ ATPase isoform expression following swimming challenges rainbow trout (Oncorhynchus mykiss). Mattina Alonge’s MS project examines how trout muscle sodium pump isoforms respond to exercise.
Na+/K+-ATPase isoform regulation in three-spine stickleback (Gasterosteus aculeatus) during salinity acclimation. Turns out stickleback respond to salinity challenges in much the same way as the often studied salmonids. They switch isoforms. Former MS student Shelby Judd tells us how.